Our genes strictly dictate our personalities, appearance and diseases. Or do they? Research has revealed that genes can turn on and off; they can be expressed for years and then silenced. Sometimes, they are never activated. And these genetic instructions—how and when DNA is read—can be determined by the experiences of one’s ancestors, even those several generations back.

This video is part of our Brilliant Breakthroughs series: our new 20-episode mini-series exploring the “Eureka!” moments and proud accomplishments of the greatest scientific minds of our time. Join us …

Brian Greene engages physicist and former LIGO spokesperson Gabriela González in a conversation about LIGO and Virgo’s new announcement of the most massive gravitational wave source to date and discusses …

Scientist and author Julian Barbour joins Brian Greene to explain his heterodox views on the nature of time, entropy, and cosmic origins. This program is part of the Big Ideas …

Extra dimensions of space — the idea that we are immersed in hyperspace — may be key to explaining the fundamental nature of the universe. Relativity introduced time as the fourth dimension, and Einstein’s subsequent work envisioned more dimensions still — but ultimately hit a dead end.

As computers become progressively faster and more powerful, they’ve gained the impressive capacity to simulate increasingly realistic environments. Which raises a question familiar to aficionados of The Matrix—might life and the world as we know it be a simulation on a super advanced computer?