Bruce Cuthbert, Ph.D., was named director of the Division of Adult Translational Research and Treatment Development (DATR) at the National Institute of Mental Health (NIMH) in 2010. A major component of this position involves coordinating the new Research Domain Criteria project to develop neuroscience-based criteria for studying mental disorders. Cuthbert returned to NIMH following four years as a professor of clinical science at the University of Minnesota. He first came to NIMH in 1998, and was from 1999 to 2005 chief of the Adult Psychopathology and Prevention Research Branch. Cuthbert earned a Ph.D. in clinical psychology and psychophysiology from the University of Wisconsin at Madison. He served in the U.S. Army Medical Service Corps and was on the faculty for seventeen years at the University of Florida. He was elected president of the Society for Psychophysiological Research in 2004 and is a fellow of the Association for Psychological Science. Cuthbert’s research interests focus on the translation of new psychophysiological models and measures of emotion to mood and anxiety disorders (and their co-morbidity). At Florida he was a senior member of Peter Lang’s research group, conducting basic studies to develop paradigms and measures for studying emotions such as the International Affective Picture System (IAPS, a standardized emotional stimulus set) and the use of the startle probe and event-related potentials as indices of emotional response; and translating the results of this work to clinical studies designed to explicate similarities and differences in psychopathology among different types of anxiety disorders.