Rob DeSalle works in molecular systematics, microbial evolution, and genomics. His current research concerns the development of bioinformatic tools to handle large-scale genomics problems using phylogenetic systematic approaches. DeSalle has worked closely with colleagues from Cold Spring Harbor Labs, New York University, and the New York Botanical Garden. He has curated several special exhibitions at the American Museum of Natural History and is co-curator of the Hall of Human Origins. Since earning his Ph.D. from Washington University, DeSalle has served on the faculties of Yale University, the City University of New York, New York University, and Columbia University.