Born in the American Midwest, Christof Koch grew up in Holland, Germany, Canada, and Morocco. He studied Physics and Philosophy and was awarded his Ph.D. in Biophysics. In 1987, Koch joined the California Institute of Technology as a Professor in Biology and Engineering. After a quarter of a century, he left academia for the Allen Institute for Brain Science in Seattle, where he is now President and Chief Scientific Officer, leading a decade-long, large-scale effort to build brain observatories to map, analyze, and understand the mouse and human cerebral cortex. Koch has authored more than 300 scientific papers and five books concerned with the way computers and neurons process information and the neuronal and computational basis of visual perception. Together with his longtime collaborator, Francis Crick, Koch pioneered the scientific study of consciousness. His latest book is Consciousness: Confessions of a Romantic Reductionist.