Researching the theoretical and practical impact of computational systems that perceive, learn, reason, and reflect, Eric Horvitz has pursued principles and methods that enable computing systems to reason about their own cognition and to make decisions amidst the complexities and uncertainties of an “open world.” Practical applications include designs for more natural interaction with computers, methods for automating medical diagnoses, predicting traffic flows, and improving search and information retrieval, and endowing computers with the ability to make decisions in time-critical situations. Horvitz forecasts that, in 50 years, our lives will be greatly enhanced by the fruits of a “computational revolution” and that people will consider many computing applications in their midst as “intelligent.” He also predicts that machine intelligence will serve a critical role in the delivery of healthcare and education, and that robotic scientists will make breakthroughs in the realms of energy, environment, and core sciences like neurobiology. Horvitz is the Immediate Past President of the Association for the Advancement of Artificial Intelligence (AAAI) and a Technical Fellow at Microsoft Research. He received his Ph.D. and M.D. from Stanford University.